Wu Tsai Human Performance Alliance Seminar
Speaker: Nick Pancheri, University of Oregon
Title: TBD
Speaker: Sarah DiIorio, Stanford University
Understanding Mechanisms to Reduce Achilles Tendon Fibrosis
Abstract:
Tendons are key to effective movement and often undergo chronic overuse or acute tear injuries. After injury, low vascularity and cellularity lead to compromised mechanical properties and scar tissue formation, called fibrosis, in the healing tendon. Despite the vast clinical burden, the specific cells responsible for tendon fibrosis are not well understood. We employed a mouse model of Achilles tendon fibrosis to identify these cell populations and the corresponding mechanisms of tendon fibrosis. This talk will present our histological and transcriptomic findings and discuss the validation of our pathways of interest which contribute to tendon scarring.
About the Seminar Series
The seminar series features speakers from across the institutions that make up the Alliance, covering topics related to our mission of uncovering the principles of performance and translating them to improved performance and care of athletes and all people.
The goal of the seminar series is to foster scientific exchange and the formation of new research collaborations through a set of research talks that are clear and compelling to researchers from a broad range of fields.
Please contact humanperformance@stanford.edu with any questions.