BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Human Performance Alliance at Stanford University - ECPv6.17.4//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Human Performance Alliance at Stanford University
X-ORIGINAL-URL:https://humanperformance.stanford.edu
X-WR-CALDESC:Events for Human Performance Alliance at Stanford University
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/Los_Angeles
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20240310T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20241103T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20250309T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20251102T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20260308T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20261101T090000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250926T120000
DTEND;TZID=America/Los_Angeles:20250926T130000
DTSTAMP:20250923T212153Z
CREATED:20250905T172137Z
LAST-MODIFIED:20250923T212153Z
UID:6136-1758888000-1758891600@humanperformance.stanford.edu
SUMMARY:Wu Tsai Human Performance Alliance Seminar
DESCRIPTION:RSVP \nSpeaker: Nicos Haralabidis\, Stanford University \nSimulations Reveal How Touchdown Kinematic Variables Affect Top Sprinting Speed: Implications for Coaching\nAbstract: Coaches often target kinematic variables\, such as horizontal touchdown distance (HTD) and inter-knee touchdown distance (IKTD)\, when they are working to increase the top sprinting speed of athletes. However\, prior findings on how HTD or IKTD affect top sprinting speed are conflicting\, potentially due to existing studies relying on experimental inter-athlete study designs. In this talk\, I will present results from a recent study that used predictive simulations to isolate how modifying HTD or IKTD influences top sprinting speed. \nSpeaker: Manoj Hariharan\, Salk \nDNA Methylation Dynamics in Skeletal Muscle Cell-types in Response to Endurance Exercise\nAbstract: DNA methylation is an epigenetic modification that is known to regulate gene expression through the addition or removal of a methyl group on specific cytosine residues of DNA. Its role in muscle function\, such as satellite cell activation\, fibertype maintenance\, and metabolic specialization\, are well-studied. Given the heterogeneity of muscle\, we implemented a genome-wide methylation assay to identify the DNA methylation dynamics of three different muscle tissues at single-nucleus resolution. The unique methylation profiles of groups of nuclei showed methylation signatures in canonical marker genes of various cell-types\, also supported by single-nucleus-resolution transcriptomics. In this talk\, I will highlight novel cell-type markers\, and differential methylation across sedentary and active animals\, at the level of the genome\, genes\, and regulons. Use of both female and male mice enabled the determination of sex-specific changes in endurance exercise\, which will also be covered in the talk. \n\nAbout the Seminar Series\nThe seminar series features speakers from across the institutions that make up the Alliance\, covering topics related to our mission of uncovering the principles of performance and translating them to improved performance and care of athletes and all people.  \nThe goal of the seminar series is to foster scientific exchange and the formation of new research collaborations through a set of research talks that are clear and compelling to researchers from a broad range of fields. \nPlease contact humanperformance@stanford.edu with any questions.
URL:https://humanperformance.stanford.edu/event/wu-tsai-human-performance-alliance-seminar-series-2025-26sept/
LOCATION:Clark S360\, Stanford University
CATEGORIES:Seminars
END:VEVENT
END:VCALENDAR